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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e5127b78a103b617889286dbec9f66f10b1dc2a1f4bee851f1ecee5d21106f' 
  AND token = 'H0aHOM/++DzuoaGOjm10ERhWVoQQbqsBEWrnutS6cGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}