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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0efb599fbf5c23798b521d2170430b9e145385a503c4d12ec586c774be90c21' 
  AND token = 'mEp/m5eYBovkvQWNQgTeQcQe5XrlBvU6h3uu2hy9GKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}