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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a03651100bc16d5e82681b62429cc5d40e0197ecf2c54bd6fa053ecce5bf8d' 
  AND token = 'l/sIwpsoVacZwetB01uXPqzRiKpmtgJ+rSD+FNRQ+b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}