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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9750fe9d5272d8352000b1237e02a665c56ed2b224230985c386bac8d8eec7bb' 
  AND token = '0tXEE8+IbXgaWY5DUpAhXDdD5fFt85XgeQIFfVQTUAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}