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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4646e2c0b157fa819ce3175d786f1d231c12a76ca737142804b54acb727935a0' 
  AND token = 'RuWxPTK4zOQLofiU2HZAyUrtmU2tMb5uQ5m09w+MlOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}