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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01fd501ec51bab4ea7afe59f4e923be94e7bc1f4132997f21fb40d8625e42730' 
  AND token = 'zxSEC9cZM/UZi6hCKtVJ9GsAZl549KfvY8S3Bpsfz/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}