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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5449da779e59ee6bb5fd2eb915fd8b9ee9d9a3e248661123f9280970844a0808' 
  AND token = 'H0FXjk3AxW0+D76riNa+GkQHfOs8HwhPjfxqpTEdCKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}