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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5c4cb3e8d5a8807abf7eb56d64741515e4597063db78721e2c1bc638a96835' 
  AND token = 'umSYzUQTRnFDC+1WLEumCBfeLRQEsl9uL9fZF7NlROM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}