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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111ed47c333ff027ad4591efd0bedb5f6e2ff688656a89042229723c818923c2' 
  AND token = 'Aw7SzPYRBy8lu2Z7AHDZruTsgqxs+L4LdcK7PcQtcCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}