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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a12b27588fc806fd25489da2e4399628d11b531a4352d9607170aa67cd20a50' 
  AND token = 'lKv7L0FW77DP03wy+XJt0CfN7tcFqeA2Q+cyZCSi8TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}