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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d849d162b8f8b2a2f1b7a1a5b78a5f3b687f1482c939c0c2f084d2cf874dcd6' 
  AND token = 'Piy/PXUmqSfdIC/N9vnYj7TmWbfBUYfbe/srxgA3kAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}