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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c621ca3e5a88bad8fce89f3556db7b34466c1155a8de592a6cc51da83c9ec83' 
  AND token = 'ODl4uauCi46ThDRxwwc1Y81gPqP/b+IL5/jhJGVJuN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}