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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378f51636f0339bc59e17feb505ac2a4ec5d4d9d7ecbde7ae759a87587787377' 
  AND token = 'j7qdcg1ETd0re3cRAOnRsmgBH7tfBs0JEiGTYEILr/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}