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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0ee6bee631004943d7b9b7b1ed332b286a41005a0bc00c537cc86445cb8cbf' 
  AND token = '43RAzyhbL8Ky6vL8pUyr74weSBoeN+xFV5JXjQWHjNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}