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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5019b9c35dc348655d928d263ddeaf9e2cd77238e9833651b39b996b615b0b7' 
  AND token = '7D7Sbc5Po1GlFT2zFQTIYMC7XY27ykS/1JxXDLhRzQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}