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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aff7289ca70593b96aeb2aa99c1293b0af0b1239a74b798bfd498434a21ff0dc' 
  AND token = 'u5+ZsaITXQM66RYOJC5TdnydtQubELeuRffVZxJfPAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}