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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6780e0b2ef7513912bbc055b3b85a06bc879b1422e85edf962d2dfa4760e8051' 
  AND token = 'b/4o7LAPmti1FbaJqN6rN09HBc0vqVTwTdT0MUzzEXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}