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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6716a3c32f2b17ad5d3f4047a97becf5a4ede5f05837be3795f799a0a4a63408' 
  AND token = 'ONZC766+PGgE757gIb2O+eQcTqtXTBozH93X4DLykzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}