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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2477486420a474212896391d82d1efa829f0f25cde3f4dee01d74944471bdcc0' 
  AND token = 'YcwuJ9qvwfCaSRTL2a4zmbd1bR0c/XVUIxsELjFxqVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}