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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e64895afb2089727254f4787ea6e018e38671d4247e1bfc93cdb870bd22f9b' 
  AND token = 'Ne9V5n8f03KnQ1c8GbSHYN+jy4UjECcrheHTTq2PpXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}