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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd25fd2f3b59080357fa28ef7b11c96b708a66e7242c2839b95d74265ca31ec5' 
  AND token = 'qLQzoLkynYd+fcBcz1RWQDaa37HdEsMRiQtDzD+ShQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}