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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0a0880ad429f749a38667defb27d9e42b5d39c959a641ca05929b91a85c87c' 
  AND token = '9x/TAvYDH11cNzynFk+StvTjmRT4eeuz53vBkL2XtoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}