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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1572d9e6dbe10b9b76677a52b60e965222aa3855aa362c972bb308bb79bcd9' 
  AND token = '444OsOcm/ProYoo0fELlypwitw3R0GBHbL4ljEqVDuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}