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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499c4bd40f9361d3799f5db536d00f7b7ab5747f9f8e3a5a1dd12a322b3b43d4' 
  AND token = '40Romn6PQgh8FZmlkw+stVeL+EPVhQLhbHxQa1FJQyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}