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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420506869d3d27f9a074765fdaa02898381e98934233959d703eb822f8f615a9' 
  AND token = 'YQlhQ5OP6jAbU/9XP3SV+d2hkSbtqpm2k/EuCYsfYes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}