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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c259afdb433137e5802106fb80c1e1f27f83535078a0d25e367e8c88d6f72af4' 
  AND token = '1gKIiU3WOGKTjhqKTyB+dNc70tbjdSUEVFtAsdpFdV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}