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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21e6cd1d7d543ed7832465e13be0013ef0bcb5cf0542d753da1d4279b2b812c' 
  AND token = 'he/FXu4dlWtR7RZRM4R4IHIQtcBZuT3L8weaGzR63Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}