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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a378b917f1f29a75d0c5257476e5efa08f39f4b3d7b3647495a6cb94c9e1a703' 
  AND token = 'ZsZ8n2akZwWnEEUuaGcviUJO0epvvBp+T4z/28jH9k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}