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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41f232ad9dd43ca42a1b80ea13b80e607566eebbe5980c0be034d6ddcd52ac7' 
  AND token = 'PyBjd1rAu4czx/5o+MZLaG3eLyU4LgEBK/xUQmi6WMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}