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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cccd58b22e1c06b50b0fbfb9c73a8b03fab366d56c2228388173b8c5f15da78' 
  AND token = 'lVwjJ/FNHLMpteIY5OehLeTCj4cxs/cAop8DSI7a6CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}