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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd621448e7df91ec7725b8ceb78b5ca36dd734fe156b7a00806e43f3ad79716' 
  AND token = '6hkOuO+Ud0OfXujq8Dhm0xh4P3nFphdLeVJevXsNQSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}