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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43148dcdf66e45b36515215ce076d6b0ada4c66958622b76bc7bc9e46c6cf33c' 
  AND token = 'aX2F+nenW8DrMPqCgCF7wiaQrVyGgns/bAq47AfbWCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}