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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386fccaedb2632aa8b7a3dce6fb32a2cd38806346aad369ec02a167e37d095b4' 
  AND token = '9v4+ThIa1qFG1L7lRbCG1YjuVHpnrozhBo+Gh3s/rcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}