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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc12c81997277123a2e8cc25dd5b6d9d133567f87268e480987ff8c102fc7378' 
  AND token = 'UG7oTEcSfv8S43rA5coSsFHRH8qBrc8kBa8fVM++lUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}