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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9edb8944df0a42edbc4e209abca2e815e8170890a96ca8159b2f47e14cfb1a78' 
  AND token = 'qTfETpzskzwErhx3Xq1Hm2HmIHnBVCEdbtpb0xiR+AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}