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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e87b2f6664f4a8b6ab8a2717bfae7d2ce1e0aa3b07742cd39ed0300461804b' 
  AND token = 'wN5ZzgJ2/Vzum5QKGZdaGCf3W7UftXa/NlQ8BMVSzs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}