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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a6ffa2c7b95887e3c7045b92021c83e448a806e09a835336f583a9d524668a' 
  AND token = 'mVPFz/JnNQWO92JjSuNy5I1Fb1HpTG6Mju7VlMhsUAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}