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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121d5f08383fa99d82ef3b3070ccfc8c475eec024e94e582fd00d1fc516e849f' 
  AND token = 'H+HhbJaTH+ehF1cF3IfzF8qC61TtYOuACtw/Nkq18pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}