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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d0dc6b139e3802ee2c844346e4dd2bc88686dbba4df8fc165dbc719102922a' 
  AND token = 'r8CPQ00SVPN9b3wLD2ZV2/LAXcn2yZtvdxe4t/v6wmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}