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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219a32110ade8c059fa96454b5c46cff557c7d016980802f7b56f2a1a15b7fd2' 
  AND token = 'reRap6VhfMgvx1Bouto8A0DwkPUY10TzLQywyrH5fDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}