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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b46002c097f8376c01e92ec798eda54fbad2eafdcf1c53bee1fcc826a2a60e' 
  AND token = 'R3ycdjpnl22Z9j/Qw2XXEnZPq5bMiN2BdEJ0obw9Zuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}