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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c2c56ed26b12ebe219667b438328cbd5348282c3763b21a03a73cd5eb2351c' 
  AND token = 'JuMXnkW5p2UAH1XMjoZSo2dmgHHtkJXvHcZmBm6mfDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}