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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80ecbb5ef66882002b5066af9afea34abb9424434ed7d2e149adfff24066f1b' 
  AND token = 'UlL8KVcyVfefM7THL0AylSLPEgrmCoz4tQ43rlgXV78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}