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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ff98932098917e096cb05bd1ff4c2fb91ef11e99a1b89db2702e14a4b3df21' 
  AND token = 'e+2tHlI8IAqVIxTjoxDXkrEIGpwuv48swC8nmgZxuf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}