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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fdd74ebb7abd33f2b71df20117b2cc4b9d06303ca1345389ac0746c7d6ef60' 
  AND token = '4NtYKimWlB7lxV48LM2x3XWP0uTBLrTCIfng1CPFQ0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}