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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05c72c7c23e8beb562e56fb039a2ed311c3258b7780b24b19dca38d0470d60dd' 
  AND token = 'ZeOtM0QhtOFpENjyBYDK7LsT6V1TaIhhxQCveyeDqN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}