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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729cac23a451a5bc6f636e46e15beb54b454e9e60b3882c505034c6ce5f49526' 
  AND token = '38oBWbHn+U6qMYJH3DkJEpLDZ1lAApDHYj4IP4YSiig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}