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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22802d918ccf183fdce540691daae8e42978df77a7129a8ecd4e43a259fa1355' 
  AND token = 'Gxa7e3BS8Qw+ORc0oeIk8yqU6pcmIiNdmJAg/qa2+W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}