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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ece705591679b0ee5a5682650c5f1b5ab20b1a0da0fc73442466bab116e4ab' 
  AND token = '+ZCoa9uCtoKkamzn2FT6lUQ4jWifg6CVyKLtjs4yH90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}