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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a106aaa9e78a6e20e9a4e7db7546520182bda6d91e2d80345fb7d0a6b44aaed3' 
  AND token = 'ioKXFIv3+Cm75zoqvxCBkXS5OcIZngWKAkpbiwg/xSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}